قسم الكيمياء الطبيه

     يهتم قسم الكيمياء الطبية بموضوعات كيمياء الدواء وتخليق المركيات الكيميائية المستخدمة كأدوية، وكيفية تحللها داخل جسم الإنسان، والمجموعات الدوائية القائمة على تركيب كيميائي متشابه، كما يتركز البحث العلمي في قسم الكيمياء الطبية على تناول التقنيات الحديثة المستخدمة في تصميم الدواء وتعديله كيميائيا بحيث يستهدف مستقبلات محددة داخل الجسم.


الاسم
الدرجة العلمية
المنصب الاداري
حالة العمل
السيرة الذاتية
سامية مصطفى
استاذ
رئيس القسم
 
          cv 
اسماعيل عوض الله سلامة محمد
استاذ
عضوا
 
            cv
محمد ابوالحسن هلال
         استاذ مساعد
عضوا
 
محمد جمعة
استاذ مساعد
 
 
خالد محمد درويش
مدرس
 
 
محمد صالح الجاويش
مدرس
 
 
صفاء عوض الله كشك
مدرس مساعد
 
 
منار ابراهيم ناجى
معيد
 
 
 


 
                              


Courses offered by the Department of Medicinal Chemistry
PTMC 301: Medicinal Chemistry (1)     كيمياء طبية 1
Topics  cover Nomenclature, synthesis, assay, medicinal uses, structure modification in related to biological activity, mode of action of the drugs belonging to the following therapeutic classes; Antimalarials, Anti-trypanosoma, Anti-lieshmania, Anti-amoeba, Anthelmenntics & Local Disinfectants. Predict the different metabolic pathway the drugs followed within the body and different factor affecting that metabolism. Predict the possible means of the lead compound designing & optimization. Also, predict the factors affecting the drug-receptor interactions.
 
 
PTMC 401: Medicinal Chemistry (2)      كيمياء طبية 2
Topics  cover nomenclature, synthesis, assay, medicinal uses, structure modification in related to biological activity, mode of action of the drugs belonging to the following therapeutic classes; Antibiotics, Sulphonamides, Antiviral, Anticancers, Oral Hypoglycemic, Diagnostic agents, Anti-mycobacterials & Antifungal.
PTMC 402: Medicinal Chemistry (3)    كيمياء طبية 3
Topics  cover nomenclature, synthesis, assay, medicinal uses, structure modification in related to biological activity, mode of action of the drugs belonging to the following therapeutic classes; CNS depressant, CNS stimulant, Narcotic analgesic, Non-Steroidal anti-inflammatory, and local anaesthetic drug.
PTMC 501: Drug design (1)      تصميم الدواء (1)
This course includes Physichochemical prosperities of drugs, Prodrug and drug latentiation, Classical and non-classical isosteres, 2D-QSAR, Pharmacophore Model, Molecular Mechanics, Quantum Mechanics, Privileged Structures and Drug – Like Molecules, Transformations to Increase Potency and the Therapeutic Index.
PTMC 502: Drug design (2)      تصميم الدواء (2)
This course includes Computer Aided Drug Design, Molecular Docking, Virtual Screening Homology Modeling, Applications of CADD in drug discovery, 3D-QSAR, CoMFA, CoMSIA.
PTMCE: Drug discovery    اكتشاف الأدوية
Topics  cover different synthetic pathway of drugs, characters, advantages and disadvantages and application of each way
 
 
 
 
 
 
 
 
Topic
Number of hours
Lecturer
Central Nervous System Stimulants
(Analeptics, Central sympathomimetics, MAO inhibitors, Tricyclic and Tetracyclic antidepressants, SSRIs and SSREs).
2
 
Prof. Dr. Samia Mostafa
Diuretics
(Osmotics, Mercury-containing diuretics, Loop diuretics, Thiazides, Potassium sparing diuretics, Purine alkaloids).
2
Prof. Dr. Samia Mostafa
Local Anesthetic Drugs 
(Mode of action, SAR, amino & esters).
2
Prof. Dr. Samia Mostafa
Autonomic Drugs
(Cholinergic agents, Cholinergic blocking agents).
2
Assistant Prof. Dr.
 Mohamed Gomaa
Autonomic Drugs Continued
(Adrenergic agents, Adrenergic blocking agents).
2
 Assistant Prof. Dr.
Mohamed Gomaa
Steroidal Hormones
(Nomenclature, Receptor, Biosynthesis, Estrogen and menopausal syndrome, Anti-estrogenic, Infertility, Breast and prostate cancer, Progesterone, Anti-progesterone, Contraceptive, Androgens, Anabolic, Anti-androgen, corticosteroids and Mineralocorticoids).
2
Assistant Prof. Dr.
Ismail Salama
Cardiovascular Drugs
(Cardiac stimulants, Anti-hypertensives, Anti-angina, Anti-arrhythmics).
2
Assistant Prof. Dr.
Ismail Salama
Anti-Hyperlipidimic
(β-sitosterol,strains, borates, bile acid  sequestrant, probucol, nicotinic acids, dextrothyroxine).
2
Assistant Prof. Dr.
Ismail Salama
Non-Steroidal Anti-inflammatory Drugs
(Salicylates, Anilines and p-aminophenol derivatives, Pyrazolones and Pyrazolidinediones, Fenamic acid derivatives, Aryl and heteroaryl acetic acid derivatives and Oxicams).
2
 
Assistant Prof. Dr.
Ismail Salama
Anti-Allergic Drugs
(Ethylenediamine, Aminoalkyl ether, Propyl amine, Piperazine, Tricyclic ring system).
2
 
Prof. Dr. Samia Mostafa
 Narcotic analgesic
(Morphine and its derivatives, Morphinans, Benzazocine, 4-phenylpiperidines, Open chain analgesics).
2
Dr. Mohamad Abo Elhassan
Central Nervous System Depressants
(General anesthetics, Sedative and hypnotics, Anxiolytics, Antipsychotics, Centrally acting skeletal muscle relaxants, Anticonvalsants).
2
Dr. Mohamad Abo Elhassan
Antiparkinsonism
(Anticholinergic and dopaminergic therapy).
2
Dr. Mohamad Abo Elhassan
Antiulcer Drugs
(H2-antagonist, Antimuscarinic, Proton-pump inhibitors, Miscellaneous).
2
Dr. Mohamad Abo Elhassan
Revision
2
Assistant Prof. Dr.
 Mohamed Gomaa
 
Practical Course
Topic
Number of hours
Demonstrator / Assistant Lecturer
Assay of Aspirin
(Direct and indirect methods)
2
Assistant Lecturer/ Khaled Darwish
 Assay of Aspirin
(Bromometric method)
2
Assistant Lecturer/ Khaled Darwish
Assay of
Chloral hydrate
2
Assistant Lecturer/ Khaled Darwish
Assay of Alkaline nasal wash
2
Assistant Lecturer/ Khaled Darwish
Assay of Novalgin®
2
Assistant Lecturer/ Khaled Darwish
Assay of Tribromide mixture I
2
Assistant Lecturer/ Khaled Darwish
Assay of Tribromide mixture II
2
Assistant Lecturer/ Khaled Darwish
Assay of Rehydran-n®
2
Assistant Lecturer/ Khaled Darwish
Assay of  Theophylline
2
Assistant Lecturer/ Khaled Darwish
Assay of Calcivit®
2
Assistant Lecturer/ Khaled Darwish
Assay of Eye dropsI
2
Assistant Lecturer/ Khaled Darwish
Assay of Eye dropsII
2
Assistant Lecturer/ Khaled Darwish
Revision
2
Assistant Lecturer/ Khaled Darwish
Practical exam
2
Assistant Lecturer/ Khaled Darwish
 
 
Topic
Number of hours
Demonstrator / Assistant Lecturer
Introduction to pharmaceutical and medicinal chemistry
2
Assistant Lecturer/ Safaa Kishk
Introduction to limit test
2
Assistant Lecturer/ Safaa Kishk
Limit test for chloride in sodium sulphate and sodium thiosulphate samples
2
Assistant Lecturer/ Safaa Kishk
Limit test for chloride in potassium permanganate and iodine samples
2
Assistant Lecturer/ Safaa Kishk
Limit test for sulphate according to E.P.
2
Assistant Lecturer/ Safaa Kishk
Limit test for sulphate according to B.P.
2
Demonstrator / Manar Nagy
Limit test for iron
2
Demonstrator / Manar Nagy
Limit test for lead according to E.P.
2
Demonstrator / Manar Nagy
Limit test for lead according to B.P.
2
Demonstrator / Manar Nagy
Limit test for Heavy metals
2
Demonstrator / Manar Nagy
Revision
2
Assistant Lecturer/ Safaa Kishk
Classwork and presentation
2
Demonstrator / Manar Nagy
Revision
2
Assistant Lecturer/ Safaa Kishk
Demonstrator / Manar Nagy
Limit Test  practical Exam
2
Assistant Lecturer/ Safaa Kishk
Demonstrator / Manar Nagy